Umuhanga mu bya siyansi
Wenqiang Yu, impamyabumenyi y'ikirenga.
●Umuyobozi mukuru wa gahunda yigihugu "973";
●Umwarimu washyizweho byumwihariko muri gahunda ya Chang Jiang Scholars;
●PI, Centre for Epigenetics, Institute of Biomedical Science University Fudan;
●Umushakashatsi washyizweho byumwihariko akaba n'umugenzuzi wa dogiteri wa kaminuza ya Fudan;
●Umuyobozi wa Komite Impuguke ya Methylation Marker ya Komite ya Tumor Marker ya shyirahamwe ry’abashinwa barwanya kanseri.
Mu 1989, yarangije muri kaminuza ya kane y’ubuvuzi ya Gisirikare maze ahabwa impamyabumenyi ihanitse mu buvuzi;
Mu 2001, yabonye impamyabumenyi y'ikirenga ya kaminuza muri kaminuza ya kane y’ubuvuzi ya Gisirikare;
Kuva 2001-2004, yabonye Postdoctoral mu ishami ry’iterambere n’irondakarere, kaminuza ya Uppsala, Suwede;
Kuva 2004-2007, yabonye Postdoctoral mu Ishuri Rikuru ry’Ubuvuzi rya Hopkins, muri Amerika;
Kugeza ubu, Porofeseri Yu ni PI akaba n'umushakashatsi mu kigo cy’ubumenyi bw’ibinyabuzima cya kaminuza ya Fudan, akaba n’umuyobozi wungirije w'ikigo cya Genomika na Epigenomika ya kaminuza ya Fudan.Ibyo yagezeho mu bushakashatsi yari yasohotse mu binyamakuru mpuzamahanga byo hejuru nka,Kamere, Kamere KamerenaJAMA.
yifuje mu binyamakuru mpuzamahanga byambere byamasomo nka Kamere, Kamere Kamere na JAMA, hamwe nibintu byinshi byagize amanota 38.1.
Umuyobozi mukuru
Lin Hua
Impamyabumenyi yubukungu ya Shanghai JiaoKaminuza ya Tong.Yabaye umuyobozi mukuru w’ishami ryashyizwe ku rutonde n’ishami rya Guosen Securities, umufatanyabikorwa wa XIANGDU CAPITAL, umufatanyabikorwa washinze CHOBE CAPITAL.Nkumuyobozi witsinda, yazamuye gushora imari mubigo byinshi byatsinze.
ObiO (688238): CGT CDMO ikora ifite ubushobozi bunini;
Novoprotein (688137): utanga ibikoresho fatizo yibanda kuri proteine recombinant;
Leadsynbio: isosiyete iyoboye ibinyabuzima bya sintetike;
SinoBay: ibigo bivura ibibyimba bigamije
Quectel (603236): uruganda runini rwitumanaho rudasanzwe rwitumanaho
XinpelTek: kwibanda kuri enterineti ya PA RF chip;
DGene: kwibanda kuri enterineti ya 3D
Video ++: uruganda rumwe muri AI
Hamwe n’imyaka irenga icumi ku isoko ry’imari, Madamu Hua yakusanyije uburambe bukomeye mu micungire y’ishoramari n’ishoramari.
Umuyobozi wa R&D
Wei Li, impamyabumenyi y'ikirenga.
Muganga Li amaze imyaka icumi akora nk'umushakashatsi wungirije muri Institute of Biologiya Science Fudan.Yayoboye imishinga 3 yubushakashatsi harimo na National Science Science Foundation y'Ubushinwa，ubushakashatsi bwigenga Umushinga wo kumenyekanisha impanona n'ibindi.Yitabiriye kandi imishinga myinshi yigihugu, harimo umushinga wigihugu 973, Umushinga wingenzi wa Fondasiyo yubumenyi Kamere nibindi.Yasohoye impapuro 16 za SCI nkumwanditsi wambere cyangwa umwanditsi uhuye naUbushakashatsi bwa Genome, eBiomedicine, Acide ya kirimbuzi Ubushakashatsi nibindi.(Igiteranyo Cyingaruka Zingaruka 158.97).
Inyungu nyamukuru zubushakashatsi:
1. Gutezimbere algorithm ya epigenetike hamwe nubushakashatsi bwinshi bwibibyimba bitera indwara.Ihuriro rimwe ryibanze ryibanze rya ADN ya methylation ikurikirana (WGPS algorithm) yashizweho mugihe cyambere.Noneho ikarita ya mbere yuzuye ya ADN methylation ikarita ya selile yumwijima yabantu.Hagati aho, yatanze uburyo bushya bwo gukuramo ibibyimba gene gucecekesha epigenetics.
2. Erekana biomarkers yimyitwarire mibi muburyo butandukanye bwa kanseri ukoresheje data-omics data.Dushingiye ku buryo bwa WGPS, twerekanye ibimenyetso byihariye bya hypermethylation hagati yibibyimba nibisanzwe.
3. Ubushakashatsi ku ndwara ya gene transcription ya gene yakozwe na NamiRNA: Icyiciro cya miRNA ya kirimbuzi, twise NamiRNA (Nuclear Activating miRNA).
Ubuvuzi R&D Ingeneri
Meigui Wang, impamyabumenyi y'ikirenga.
Muganga Wang yakiriye impamyabumenyi y'ikirenga.impamyabumenyi yakuye muri kaminuza y’ubuvuzi y’amajyepfo mu 2019. Yakomeje kandi amahugurwa asanzwe atuye mu bitaro bya gatatu bishamikiye kuri kaminuza ya Sun Yat-sen (2019-2021).Ibyifuzo bye mubuvuzi ni ugupima no kuvura kanseri yo mu mutwe no mu ijosi nka kanseri yo mu kanwa na kanseri ya nasofaryngeal.Inyungu zubushakashatsi yibanze ku gusuzuma hakiri kare kanseri ya nasofaryngeal.
Ubuvuzi R&D Ingeneri
Yaping Dong, Ph.D.
Muganga Dong yabonye impamyabumenyi y'ikirenga.Impamyabumenyi mu miti y’ubuvuzi yakuye muri kaminuza y’ubuvuzi ya Fujian mu 2020, anakora ubushakashatsi nyuma ya dogiteri mu kigo cya kanseri cya kaminuza ya Fudan ya Shanghai kuva mu 2020 kugeza mu wa 2022. Nk’umuntu witabiriye uruhare runini, yitabiriye imishinga myinshi y’igihugu, harimo na Minisiteri y’ubumenyi n’ikoranabuhanga Gahunda nyamukuru ya “ Iterambere rikomeye ry'ibiyobyabwenge ", Ikigo cy'igihugu gishinzwe ubumenyi kamere mu Bushinwa n'ibindi.Yasohoye impapuro nyinshi zujuje ubuziranenge muri Acta Pharmaceutica Sinica B, Acta Pharmacologica Sinica na Radiyo Oncology.